Possible but not recommended. Improperly designed systems can fail to lower radon, increase moisture damage, or create back-drafting hazards in combustion appliances (water heaters, furnaces). Ohio licensure exists for these reasons.
More detail
DIY radon mitigation is technically legal in Ohio (no licensure currently required for residential radon work) but commonly produces three failure modes. First, undersized fans that fail to reach the EPA-recommended suction (need at least 0.5-1.0 inch water column negative pressure under the slab) and leave the home above 4.0 pCi/L despite the install. Second, oversized fans that over-pull and back-draft natural-draft combustion appliances, creating carbon-monoxide risk. Third, code-non-compliant routing (stacks terminated below roofline or near operable openings) that real-estate inspections later flag, requiring rework. Material cost for DIY is roughly $400-$700 (4-inch PVC, fan, manometer, polyurethane caulk, electrical); labor for a Cincinnati-area install adds $800-$1,800 to that. Most homeowners conclude the labor delta is worth it for the warranty, the credentialing, and the 48-hour verification retest. Cincinnati real-estate inspection reality: when a non-permit DIY mitigation system is identified during a sale-time home inspection, the buyer's lender often requires a credentialed mitigator to inspect, certify, and (if needed) bring the system to code before closing. That rework cost typically lands in the $400-$800 range and falls on the seller. DIY systems that pass inspection have to meet the same code standards as professional installs.